| 发明名称 |
METHODS OF TREATING DIABETES BY ADMINISTERING A GLUCAGON RECEPTOR ANTAGONIST IN COMBINATION WITH A CHOLESTEROL ABSORPTION INHIBITOR |
| 摘要 |
Use of a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor for the treatment of diabetes and related conditions is disclosed. |
| 申请公布号 |
US2015320724(A1) |
申请公布日期 |
2015.11.12 |
| 申请号 |
US201314649651 |
申请日期 |
2013.12.08 |
| 申请人 |
GUAN Hong-Ping;CASTRO-PEREZ Jose M.;DAVIS Harry R.;ENGEL Samuel S.;JOHNS Douglas G.;LIN Songnian;PREVIS Steven F.;RODDY Thomas P.;WANG Liangsu;WANG Sheng-Ping;XIONG Yusheng;MERCK SHARP & DOHME CORP. |
发明人 |
Guan Hong-Ping;Castro-Perez Jose M.;Davis Harry R.;Engel Samuel E.;Johns Douglas G.;Lin Songnian;Previs Stephen F.;Roddy Thomas P.;Wang Liangsu;Wang Sheng-Ping;Xiong Yusheng |
| 分类号 |
A61K31/4184;A61K31/194;A61K31/403;A61K9/24;A61K31/397;A61K31/415 |
主分类号 |
A61K31/4184 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of treating diabetes in a mammalian subject which comprises administering to said mammalian subject:
(a) a glucagon receptor antagonist, and (b) a cholesterol absorption inhibitor; wherein the mammalian subject has an LDL cholesterol plasma level of less than 130 mg/dL. |
| 地址 |
US |
