摘要 |
<p>The present invention provides an inexpensive and efficient method for a producing (1R, 2S)-1-amino-2-vinylcyclopropanecarboxylic acid ester, which is useful for an intermediate of drugs. (1R, 2S)-1-amino-2-vinylcyclopropanecarboxylic acid ester derivative, which is improved optical purity, is produced by forming the salt from 1-amino-2-vinylcyclopropanecarboxylic acid ester which is racemic or has low optical purity and the optically active carboxylic acid, and precipitating the salt as a solid from a solvent.</p> |