Mitochondrial penetrating peptides as carriers for antimicrobials

摘要

There is described herein compounds comprising a mitochondrial penetrating peptide (MPP) conjugated to an antimicrobial, and their method of use.

主权项

1. A composition comprising a peptide comprising the amino acid sequence of SEQ ID NO: 7, conjugated to 5-fluorouracil, gemcitabine, azathioprine, mecaptopurine, methotrexate,raltitrexed, pemetrexed, 2-deoxyglucose, 3-bromopyruvate, oxamate or 6-aminonicotinamide.