摘要 |
This invention encompasses compounds of formula (I) and the stereoisomers and pharmaceutically acceptable salts thereof. In formula (I) R represents lower alkyl of 1 to 6 carbon atoms, lower alkenyl of 2 to 6 carbon atoms, or -(CH2)m-R<3> wherein R<3> represents cycloalkyl of 3 to 5 carbon atoms and m is 1, 2 or 3; R1 is -CONH2 or alpha wherein R2 is lower alkyl, phenyl, unsubstituted or substituted with loweralkyl, or beta ; and n is an integer from 2 to 5. The compounds are useful anti-inflammatory agents for treating, for example, inflammatory bowel disease, rheumatoid arthritis, gout, asthma and psoriasis. |