发明名称 NEBULIZATION OF MONOCLONAL ANTIBODIES FOR TREATING PULMONARY DISEASES
摘要 Provided is the use of an antibody that inhibits activation of the complement cascade in the manufacture of a medicament for preventing or treating in a subject a pulmonary condition in which complement is activated, wherein said antibody has an active Fab fragment and a mutated Fc portion, and wherein the mutated Fc portion does not activate complement, wherein the medicament is suitable for co-administration with an additional active agent, and wherein said antibody is specific to C5, C5 convertase, C5a or C5b-9. (61) Addition to 538384
申请公布号 NZ582627(A) 申请公布日期 2011.11.25
申请号 NZ20060582627 申请日期 2006.05.10
申请人 ALEXION PHARMACEUTICALS, INC. 发明人 WANG, YI
分类号 C07K16/18;A61K39/395 主分类号 C07K16/18
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