发明名称 RESVERATROL - COPPER (II) MEDIATED DEGRADATION OF DNA AND RNA
摘要 <p>A composition comprising a plant polyphenol, especially Resveratrol, and copper (II) for the degradation of or preventing or reducing a rise in the level of one or more of circulating fragments of chromatin, DNA and RNA. The molar ratio of plant polyphenol to copper (II) is in the range 1:1 to 10-10 Higher levels of degradation of chromatin fragments, DNA and RNA occur as the molar ratio of the copper to plant polyphenol to copper (II) is reduced to an optimum level depending on the material to be degraded. The composition provides therapeutic treatment for conditions associated with raised levels of chromatin fragments including cancer and HIV, may enhance cell destruction therapies and, reduce the incidence of death of live cells in the presence of dead cells or fragments of chromatin from dead cells.</p>
申请公布号 IN1528MU2013(A) 申请公布日期 2015.06.26
申请号 IN2013MU01528 申请日期 2013.07.26
申请人 TATA MEMORIAL CENTRE 发明人 INDRANEEL MITTRA
分类号 A61K36/82;A61Q19/08 主分类号 A61K36/82
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