发明名称 |
Assays and methods for selecting a treatment regimen for a subject with depression |
摘要 |
<p>The present invention provides assays, methods and compositions for selecting a treatment regimen for a patient having depression or at risk for depression and/or treating at least one symptom of depression in the subject, based on the recognition that specific combinations of single nucleotide polymorphisms (SNPs) are associated with a therapeutic response to a folate-comprising compound. Provided herein are also methods for improving the effectiveness of an antidepressant drug administered to a subject with depression or at risk for depression by administering an adjunctive therapy of a folate-comprising compound to the subject if the subject carries a specific combination of SNPs that are predictive of a therapeutic response. Furthermore, provided herein are compositions of the folate-comprising compound.</p> |
申请公布号 |
AU2014248949(A1) |
申请公布日期 |
2015.09.10 |
申请号 |
AU20140248949 |
申请日期 |
2014.03.11 |
申请人 |
NESTEC S.A. |
发明人 |
FAVA, MAURIZIO;PAPAKOSTAS, GEORGE;KOCH JR., HAROLD O.;KRONLAGE, DAVID |
分类号 |
G06F19/22 |
主分类号 |
G06F19/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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