| 发明名称 | Stable aqueous G-CSF formulations | ||
| 摘要 | The invention relates to stable glutamate-buffered G-CSF formulations having a pH of from 3.5 to 4.8. The invention further concerns lyophilisates and powders obtainable from such formulations, and to pharmaceutical kits containing such lyophilisates and powders. | ||
| 申请公布号 | US9119789(B2) | 申请公布日期 | 2015.09.01 |
| 申请号 | US200812530671 | 申请日期 | 2008.04.04 |
| 申请人 | SANDOZ AG | 发明人 | Fürtinger Sabine;Matous Heinrich |
| 分类号 | A61K38/24;C07K1/00;A61K9/19;A61K38/19;A61K47/18 | 主分类号 | A61K38/24 |
| 代理机构 | O'Melveny & Myers LLP | 代理人 | O'Melveny & Myers LLP |
| 主权项 | 1. A stable liquid aqueous glutamic acid/glutamate-buffered Granulocyte-Colony Stimulating Factor (G-CSF) formulation having a pH of from 3.5 to 4.8, said formulation comprising a non-ionic surfactant and being essentially free from amino acids/amino acid salts other than glutamic acid/glutamate. | ||
| 地址 | Basel CH | ||