发明名称 |
TASTE MASKED ACTIVE PHARMACEUTICAL POWDER COMPOSITIONS AND PROCESSES FOR MAKING THEM |
摘要 |
A taste masked particulate pharmaceutical formulation include a core that comprises an active pharmaceutical ingredient; at least a partial nanoparticle material layer on the core that comprises a nanoparticle material with a median particle size not greater than 100 nm; a first polymer layer that is at least partially water soluble and a second polymer layer that is water insoluble. The active pharmaceutical ingredient is completely released in 30 minutes in the USP Dissolution Test. A process of making the particulate pharmaceutical formulation using sequential fluidized bed coating steps under controlled conditions is also described. |
申请公布号 |
EP2906204(A1) |
申请公布日期 |
2015.08.19 |
申请号 |
EP20130779706 |
申请日期 |
2013.10.09 |
申请人 |
NEW JERSEY INSTITUTE OF TECHNOLOGY |
发明人 |
TO, DANIEL;DAVE, RAJESH, N. |
分类号 |
A61K9/50 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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