发明名称 |
DISCONTINUOUS FLUIDIC SYSTEMS FOR POINT-OF-CARE ANALYTE MEASUREMENT |
摘要 |
Disclosed herein are systems and methods for using the controlled movement of magnetic particles using controlled magnetic fields in a fluidic device containing separated fluidic regions to detect analytes in solution by immunoassay, such as an enzyme-linked immunosorbant assay (ELISA) for various medical and scientific applications. In order to achieve sequential exposure to the different chemical environments required in an immunoassay, magnetic particles are driven through fluid-containing chambers separated by air-gaps that may take the form of air bubbles or small open-air separations, for example. Externally controlled magnets coupled to actuators draw the flow of magnetic particles through air-liquid interfaces produced by microfluidic surface tension at the air-gap, washing the particles. |
申请公布号 |
WO2015113047(A2) |
申请公布日期 |
2015.07.30 |
申请号 |
WO2015US13097 |
申请日期 |
2015.01.27 |
申请人 |
BREVITEST TECHNOLOGIES, LLC |
发明人 |
CHATTERJEE, DEV KUMAR;VARADHACHARY, ATUL;LINBECK, LEO III |
分类号 |
C12Q1/68;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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地址 |
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