发明名称 |
Stable parenteral DNJ compositions |
摘要 |
<p>A stable pharmaceutical composition that includes an active agent selected from 1-deoxynojirimycin, a pharmaceutically acceptable salt thereof, or a derivative thereof, and a buffer, wherein the stable pharmaceutical composition is capable of being parenterally administered to a human without deleterious health effects. Pompe disease is an example of a lysosomal storage disorder. Pompe disease is caused by a deficiency in the enzyme acid alpha-glucosidase (GAA). GAA metabolizes glycogen, a storage form of sugar used for energy, into glucose.</p> |
申请公布号 |
AU2014205378(A1) |
申请公布日期 |
2015.07.23 |
申请号 |
AU20140205378 |
申请日期 |
2014.01.09 |
申请人 |
AMICUS THERAPEUTICS, INC. |
发明人 |
CHAR, HING;TESLER, SERGEY;YANG, JIPING;DILONE, ENRIQUE |
分类号 |
A61K31/445 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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