摘要 |
<p>The present invention relates to novel substituted quinoline derivatives according to the general Formula (Ia) or Formula (Ib): including any stereochemically isomeric form thereof, a pharmaceutically acceptable salt thereof, a N-oxide form thereof or a solvate thereof. The claimed compounds are useful for the treatment of a bacterial infection. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the claimed compounds, the use of the claimed compounds or compositions for the manufacture of a medicament for the treatment of a bacterial infection and a process for preparing the claimed compounds.</p> |
申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
GUILLEMONT, JRME EMILE GEORGES;DORANGE, ISMET;LANOIS, DAVID FRANCIS ALAIN;VILLALGORDO-SOTO, JOS MANUEL;SIMONNET, YVAN REN FERDINAND;MOTTE, MAGALI MADELEINE SIMONE;ANDRIES, KOENRAAD JOZEF LODEWIJK, MARCEL;KOUL, ANIL |