| 摘要 |
PROBLEM TO BE SOLVED: To provide compounds, including enantiomerically pure forms thereof, and pharmaceutically acceptable salts or co-crystals and prodrugs thereof which have glucagon receptor antagonist or inverse agonist activity.SOLUTION: The present invention provides a compound represented by the formula in the figure, or pharmaceutically acceptable salts, solvates, and prodrugs thereof. [Ris H, methyl or ethyl; Ris Calkyl, alkenyl, alkoxy, Ccycloalkyl, Ccycloalkenyl, Cbicycloalkenyl, aryl or heteroaryl; L is phenyl, indenyl, benzoxazol-2-yl, Ccycloalkyl, Ccycloalkenyl or Cbicycloalkenyl; and Ris H, F, Cl, methyl, CF, OCF, or CN.] |
