COMBINED PREPARATIONS AND COMPOSITIONS FOR THE TREATMENT OF OROPHARYNGEAL PAIN

摘要

The invention relates to a composition and/or a kit for the preparation thereof and/or a combined preparation comprising a free base or any of the pharmaceutically acceptable salts thereof, in which the free base has formula (I), (in which R1 is selected from the list consisting of hydrogen, chlorine, bromine, methyl, methoxy and hydroxy and R is an alkyl radical having one or two carbon atoms), and an opioid antagonist of the peripheral mu receptors. The invention also relates to the composition, kit and/or combined preparation for use in the treatment of oral mucositis and pain associated with oral mucositis.