发明名称 POLYMERS WITH REDUCED ESTROGENIC ACTIVITY
摘要 A polymer which comprises recurring units derived from at least one monomer (M) having a general formula (I) Y1—Z1-Q-Z2—Y2 wherein Y1 and Y2, equal or different from each other, are independently selected from a group consisting of OH, SH, Cl, Br, NO2 or I; Z1 and Z2, equal or different from each other, independently comprises at least 1 aromatic ring and, Q comprises at least one hydrophilic moiety (H) selected from the group consisting of a sulfone (SO2), a ketone (CO), a phosphine oxide (PO), an ether, a thioether, an ester, an anhydride, a carbonate, an amide, an imide, an imine and an urethane group, and the interatomic distance between Y1 and Y2 is at least 10 Å, the monomer has an EC50 response value to the estrogen receptor a (ERα) equal to or at least 26000 nM.
申请公布号 ZA201308712(B) 申请公布日期 2015.06.24
申请号 ZA20130008712 申请日期 2013.11.20
申请人 SOLVAY SPECIALTY POLYMERS USA, LLC 发明人 CORBIN, GEORGE A.;BHATNAGAR, ATUL;MOORE, THEODORE
分类号 C08G 主分类号 C08G
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