| 发明名称 |
C-RAF MUTANTS THAT CONFER RESISTANCE TO RAF INHIBITORS |
| 摘要 |
Nucleic acids and proteins having a mutant C-RAF sequence, and methods of identifying patients having cancer who are likely to benefit from a combination therapy and methods of treatment are provided. |
| 申请公布号 |
US2015133478(A1) |
申请公布日期 |
2015.05.14 |
| 申请号 |
US201314387735 |
申请日期 |
2013.03.07 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE, INC. |
发明人 |
Emery Caroline;Antony Rajee;Garraway Levi A. |
| 分类号 |
A61K31/506;C12Q1/68;C12N9/12;A61K31/437;A61K31/4184 |
主分类号 |
A61K31/506 |
| 代理机构 |
|
代理人 |
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| 主权项 |
|
| 地址 |
Boston MA US |
