Substituted n-(1h-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as type iii receptor tyrosine kinase inhibitors

摘要

The disclosure relates to a substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compound of formula (I) and pharmaceutically acceptable salts thereof in which the variables R1, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of type III receptor tyrosine kinases cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal.