NEW MOLECULE ASSOCIATED WITH HUMAN METASTATIC TUMOUR, METHODS FOR DETECTING BOTH ACTIVATED GENE, AND PROTEIN, AND PREVENTING GENE EXPRESSION

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions refers to medicine, pharmaceutics and biochemistry, and concerns a metastatic melanoma grade marker containing the amino acid sequence SEQ ID NO:1. There are also declared a recovered antibody and a monoclonal antibody, which recognise human TM9SF4 protein by binding to a peptide fragment of SEQ ID NO:1, as well as a kit for determining a tumour grade comprising the above antibody, using SEQ ID NO:1 for determining the metastatic pattern of melanoma.EFFECT: group of inventions provides the faster detection of melanoma metastasis.10 cl, 8 ex, 2 tbl, 10 dwg