METHODS OF TREATING A PATIENT HAVING AN AUTOIMMUNE DISORDER BY ADMINISTERING A BAFF ANTAGONIST

摘要

Therapeutic regimens for administration of BAFF antagonists for treatment of immunologic and related disorder are described. Regimens involve a short-term BAFF antagonist administration course followed by an extended no-treatment period prior the round or administration.

主权项

1. A method of treating a patient having an immunologic disorder, comprising:
(a) administering to the patient a therapeutically effective amount of a soluble BCMA (B cell maturation antigen) polypeptide at least once or at one or more intervals of less than N weeks; (b) temporarily discontinuing the administration of step (a) for N weeks or longer; and (c) repeating steps (a) and (b) at least once; wherein N is 8, 9, 10, 11, or 12.