| 发明名称 |
IMPROVED PHARMACEUTICAL COMPOSITION CONTAINING DIHYDROPYRIDINE CALCIUM CHANNEL ANTAGONIST AND METHOD FOR THE PREPARATION THEREOF |
| 摘要 |
<p>THE PRESENT INVENTION RELATES TO THE FORMULATION OF SOLID DOSAGE FORMS COMPRISING A THERAPEUTICALLY EFFECTIVE AMOUNT OF A DIHYDROPYRIDINE CALCIUM CHANNEL ANTAGONIST SUCH AS LERCANIDIPINE OR SALT THEREOF, IN COMBINATION WITH COLLOIDAL SILICON DIOXIDE SUCH AS AEROSIL? TO ENHANCE BIOAVAILABILITY AND IMPROVE SOLUBILITY, AND A PROCESS FOR THE PREPARATION THEREOF BY WET GRANULATION. THE MOST ILLUSTRATIVE DRAWING IS</p> |
| 申请公布号 |
MY153857(A) |
申请公布日期 |
2015.03.31 |
| 申请号 |
MY2010PI00318 |
申请日期 |
2008.07.23 |
| 申请人 |
PHARMATHEN SA;RECORDATI IRELAND LIMITED |
发明人 |
KARAVAS, EVANGELOS;KOUTRIS, MAKIS;SAMARA, VICKY;MATSINGOU, CHRISTINA;ILIOPOULOU, ATHINA |
| 分类号 |
A61K9/20 |
主分类号 |
A61K9/20 |
| 代理机构 |
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代理人 |
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| 主权项 |
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