发明名称 |
CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR GAMMA |
摘要 |
The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administering these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides carboxamide containing cyclic compounds of Formula (1) to Formula (5) and the enantiomers, diastereomers, tautomers, N-oxides, solvates and pharmaceutically acceptable salts thereof. |
申请公布号 |
PH12015500142(B1) |
申请公布日期 |
2015.03.16 |
申请号 |
PH12015500142 |
申请日期 |
2015.01.23 |
申请人 |
PHENEX PHARMACEUTICALS AG |
发明人 |
GEGE, CHRISTIAN;KINZEL, OLAF;STEENECK, CHRISTOPH;KLEYMANN, GERALD;HOFFMANN, THOMAS |
分类号 |
A61K31/40;A61P1/04;A61P29/00;C07D207/34;C07D231/14;C07D249/10;C07D401/04;C07D405/04 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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