N-[(2'R)-2'-DEOXY-2'-FLUORO-2'-METHYL-P-PHENYL-5'-URIDYLYL]-L-ALANINE 1-METHYLETHYL ESTER AND PROCESS FOR ITS PRODUCTION

摘要

PROBLEM TO BE SOLVED: To provide compounds for treating viral diseases, in particular, inhibitors of RNA-dependent 5 RNA viral replication, which are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals; and methods of producing the same.SOLUTION: Disclosed herein are nucleoside phosphoramidates represented by the formula 4 and their use. [In the formula, Prepresents a chiral phosphorus atom.]