| 发明名称 |
Prolinamide derivative as thrombin inhibitor, preparation method and application thereof |
| 摘要 |
Provided are a compound of formula (I), pharmaceutically acceptable salts thereof, preparation methods and applications thereof for inhibiting thrombin, and applications in the treatment and prevention of thrombin-mediated and thrombin-related diseases. |
| 申请公布号 |
EP2824097(A1) |
申请公布日期 |
2015.01.14 |
| 申请号 |
EP20140183844 |
申请日期 |
2011.11.04 |
| 申请人 |
SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY;LI, MIN |
发明人 |
LI, MIN;SHAN, HANBIN;HUANG, YU;YUAN, ZHEDONG;YU, XIONG |
| 分类号 |
C07D207/16;A61K31/397;A61K31/401;A61P7/02;C07D295/104;C07D401/12 |
主分类号 |
C07D207/16 |
| 代理机构 |
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