| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a highly-branched polymer which has sufficient relaxation capability, has no dissociation of metal ions, is excellent in living body safety, has moderate water solubility and lipid solubility and has wide in-organ distribution and an uptake effect in organs, thus enabling imaging of wide-ranging target organ and disorders and enabling use as a new MRI contrast agent. <P>SOLUTION: There is provided a highly-branched polymer obtained by polymerizing the monomer A having an alkylene oxide group and two or more radically-polymerizing double bonds in the same molecule, and the monomer B having a portion expressing a paramagnetic property and at least one radically-polymerizing double bond in the same molecule, in the presence of a polymerization initiator C of 5-200 mol% with respect to the monomer A. The MRI contrast agent containing the polymer is also provided. <P>COPYRIGHT: (C)2012,JPO&INPIT</p> |
