DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES

摘要

A method of making an anti-Markovnikov addition product, comprises reacting an acid with an alkene or alkyne in a dual catalyst reaction system to the exclusion of oxygen to produce said anti-Markovnikov addition product; the dual catalyst reaction system comprising a single electron oxidation catalyst in combination with a hydrogen atom donor catalyst. Dual catalyst composition usefuol for carrying out such methods are also described.