发明名称 |
PALLADIUM COMPLEXES OF CURCUMIN AND ITS ANALOGUES AND METHODS OF PREPARATION OF THE SAME |
摘要 |
The invention relates to palladium(II) complexes of curcumin and its analogues of general formula (Formula (A)) wherein R1 and R2 are each independently hydrogen, hydroxy, methoxy or ethoxy, as well as the process for preparing the same by reacting the complex compounds [(tmcyda)Pd(OAc)2 ] or [(dmpip)Pd(OAc)2] of general formula ((Formula (B) with curcumin or its analogues of general formula (Formula (B)) wherein R1 and R2 are the same as defined above, in an alcohol having 1 to 4 carbon atoms, or in chlorinated solvents, selected from the group comprising chloroform and dichloromethane, for 12 to 140 hours at the temperature of 15 to 50 °C. |
申请公布号 |
WO2014175841(A1) |
申请公布日期 |
2014.10.30 |
申请号 |
WO2014SK50004 |
申请日期 |
2014.02.12 |
申请人 |
UNIVERZITA KOMENSKEHO V BRATISLAVE;CENTRUM VEDECKO-TECHNICKYCH INFORMACII SR (CVTI SR) |
发明人 |
MIKLASOVA, NATALIA;MIKLAS, ROMAN;DEVINSKY, FERDINAND |
分类号 |
C07F15/00;A61K33/24;A61P35/00 |
主分类号 |
C07F15/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|