A bioresorbable drug-eluting biopolymer suture-free blood vessel anastomosis devices can be deployed to join two blood vessels and resorbed by the body over a predetermined time period after the blood vessel has become joined. The anastomosis device can include a hollow tube that is inserted interconnect the two vessels to be jointed. A non-piercing suture is wrapped around the vessel to secure the anastomosis. The anastomosis device can include hollow tube that extends along an axis from a first end to a second end. The ends can be fitted with elements that facilitate mechanical attachment of the vessel to the anastomosis device and provide for a secure seal. The ends can include enlarged spherical tips that can be inserted into the lumen of a vessel and an outer sleeve can be used to compress the vessel between the outer surface of the hollow tube and the inner surface of the outer sleeve to provide a secure seal. The ends can also include barbs or microneedles that pierce the vessel and provide a secure seal.
申请公布号
WO2014176458(A2)
申请公布日期
2014.10.30
申请号
WO2014US35361
申请日期
2014.04.24
申请人
TRUSTEES OF TUFTS COLLEGE;BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
发明人
JOSE, RODRIGO;RAJA, WASEEM K.;KAPLAN, DAVID L.;IBRAHIM, AHMED;LIN, SAMUEL;ABDURROB, ABDURRAHMAN