MICROSPHERE DRUG DELIVERY SYSTEM FOR SUSTAINED INTRAOCULAR RELEASE

摘要

Disclosed are biodegradable microspheres between 40 µm and 200 µm in diameter that are effectively retained in the anterior chamber of the eye without producing hyperemia. The microspheres generally contain a drug effective for the treatment of an ocular condition and include a biodegradable polymer matrix that can provide for the sustained (>7 day) release of the drug following administration to the anterior chamber of the eye. Methods for making and using the microspheres to treat an ocular condition are also disclosed.