发明名称 DERIVADOS DE CARBOXAMIDA IMIDAZOLIDINA COMO MODULADORES DE P2X7
摘要 The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof: The compounds or salts modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor (P2X7 receptor antagonists). The invention also provides the use of such compounds or salts, or pharmaceutical compositions thereof, in the treatment or prevention of disorders/diseases mediated by the P2X7 receptor, for example pain, inflammation or a neurodegenerative disease, in particular pain such as inflammatory pain, neuropathic pain or visceral pain.
申请公布号 BRPI0809930(A2) 申请公布日期 2014.10.07
申请号 BR2008PI09930 申请日期 2008.04.02
申请人 GLAXO GROUP LIMITED 发明人 PAUL JOHN BESWICK;DAVID KENNETH DEAN;ROBERT JAMES GLEAVE;ANDREW PETER MOSES;DARYL SIMON WALTER
分类号 C07D233/36;A61K31/4166;A61P29/00;C07D401/04;C07D401/06;C07D403/04 主分类号 C07D233/36
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