Direct Lipid to Membrane Drug Delivery

摘要

Described herein is a method of delivering hydrophilic drugs directly from a hydrophobic carrier and/or excipient to absorbing cell membranes. More specifically, CaNa2 EDTA is delivered rectally from a suppository containing methylbutylketone in a carrier as an excipient.

主权项

1. A suppository for use in chelating heavy metals in a living being comprising:
i. calcium disodium ethylenediaminetetraacetate (CaNa2 EDTA), ii. a hydrophobic excipient, and iii. a carrier comprising one or more of glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids, cocoa butter, and fatty acids.