Methods and Pharmaceutical Compositions for Treating Celiac Disease and Gluten Intolerance

摘要

The invention concerns methods for protecting a subject in need from a deleterious effect of gluten ingestion. The invention specifically concerns the treatment of celiac disease and gluten intolerance. The invention further provides pharmaceutical compositions for protecting a subject in need from a deleterious effect of gluten ingestion, and, in particular, for treating celiac disease and gluten intolerance. Oral administration of ALV003 can protect celiac disease patients and patients otherwise suffering from gluten-intolerance from the harmful effects of ingesting food containing gluten.

主权项

1. A method for protecting a patient from a deleterious effect of gluten ingestion, said method comprising administering to said patient a dose of ALV003 in an amount ranging from 150 mg to 3 g per day sufficient to prevent said deleterious effect.