摘要 |
<p>PURPOSE: A marker for diagnosing liver diseases and a method for detecting the same are provided to early and effectively predict susceptibility with respect to liver cancer in a patient with HBV infection or to diagnose liver cancer. CONSTITUTION: A marker for diagnosing liver diseases contains a polynucleotide which is selected among: a polynucleotide with 10-200 continuous bases containing base sequences encoding one or more coding corresponding to 5^th, 83^th, 97^th, 100^th, 182^th, and 184^th mutant amino acids of core protein C region of HBV and 28^th mutant amino acid of preC region; and a complementary polynucleotide thereof. Each amino acid residue number is determined by a residue order corresponding to preC and C regions among genotypes A to H. A kit for diagnosing liver diseases contains the polynucleotide.</p> |