| 主权项 |
1. A compound of formula (I),or a pharmaceutically acceptable salt thereof, wherein
a is a single or double bond; i is 0; j is 0; h is 1, 2, or 3; m is 1; n is 0; X is O, S, S(O), or a bond; L is —[C(Ra)(Rb)]p—, —[C(Ra)(Rb)]q1—[(CRc)═(CRd)]—[C(Ra)(Rb)]q2—,—[C(Ra)(Rb)]r1—[C≡C]—[C(Ra)(Rb)]r2—, —[C(Ra)(Rb)]s-cyclopropylene-[C(Ra)(Rb)]t—, a bond or Y, wherein Y is substituted or unsubstituted monocyclic aryl or substituted or unsubstituted furanyl, imidazolyl, isoxazolyl, isothiazolyl, oxadiazolyl, 1,3-oxazolyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, pyrazolyl, pyrrolyl, tetrazolyl, thiadiazolyl, 1,3-thiazolyl, thienyl, triazolyl, or triazinyl; or X and L taken together are a bond; Q is substituted or unsubstituted monocyclic aryl, substituted or unsubstituted bicyclic aryl, substituted or unsubstituted monocyclic heteroaryl, or substituted or unsubstituted bicyclic heteroaryl; R1 is hydrogen, C1-C4 alkyl, C1-C4 haloalkyl, —C(O)—C1-C4 alkyl, —C(O)—C1-C4 haloalkyl, —C(O)O-C1-C4 alkyl, or —C(O)O-C1-C4 haloalkyl; R2 is hydrogen, C1-C4 alkyl, C2-C4 alkenyl, or C2-C4 alkynyl, wherein C1-C4 alkyl, and the saturated carbon atoms of C2-C4 alkenyl and C2-C4 alkynyl, can be unsubstituted or substituted by hydroxyl, C1-C8 alkyl, C1-C8 haloalkyl, carboxy, or alkoxycarbonyl; R3 is hydrogen, halogen, C1-C5 haloalkyl, C1-C5 alkoxy, C1-C5 haloalkoxy, or cyano; Ra, Rb, Rc, and Rd, are, at each occurrence, independently hydrogen, halogen, C1-C8 alkyl, C1-C8 haloalkyl, carboxy, or alkoxycarbonyl; p is 1, 2, 3, 4, or 5; q1 and q2 are independently 0, 1, 2, or 3, provided that the sum of q1 and q2 is 0, 1, 2, or 3; r1 and r2 are independently 0, 1, 2, or 3, provided that the sum of r1 and r2 is 0, 1, 2, or 3; s is 0, 1 or 2; and t is 0 or 1; wherein Q or Y, when substituted, are independently substituted with 1, 2, 3, 4, or 5 substituents, wherein the substituent is halogen, cyano, C1-C5 haloalkyl, C1-C5 alkyl, C2-C5 alkenyl, C2-C5 alkynyl, hydroxy, C1-C5 alkoxy, —O—C1-C5 haloalkyl, —S—C1-C5 alkyl, —S—C1-C5 haloalkyl, —SO2—C1-C5 alkyl, —SO2—C1-C5 haloalkyl, C1-C5 cyanoalkyl, or —NO2. |
