发明名称 |
Composition, device and associated method |
摘要 |
A composition includes a first probe, a first initiator component bonded to the first probe, a second probe, and a second initiator component bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte, and the first initiator component and the second initiator component are capable of forming an initiator when present in proximity to each other and when the first probe and the second probe are bonded to the analyte. An associated kit, device, and method are provided. |
申请公布号 |
US8778846(B2) |
申请公布日期 |
2014.07.15 |
申请号 |
US200711680652 |
申请日期 |
2007.03.01 |
申请人 |
General Electric Company |
发明人 |
Nelson John Richard;Moasser Bahram;Sood Anup;Grossmann Gregory Andrew;Lu Su;Pan Zhida;Qiang Liangliang;Gui John Yupeng;Cai Wei;Zheng Zhixin |
分类号 |
C40B40/04;G01N33/53;G01N33/566 |
主分类号 |
C40B40/04 |
代理机构 |
|
代理人 |
Dobson Melissa K. |
主权项 |
1. A composition, comprising:
a first probe; a first initiator component bonded to the first probe; a second probe chemically distinct from the first probe; a second initiator component bonded to the second probe,
wherein the first probe and the second probe are bonded to a single analyte such that the first initiator component and the second initiator component form an initiator, with the proviso that the first initiator component and the second initiator component are independently inactive when the first probe and the second probe are not bonded to the analyte,wherein the initiator is present between the polymer and each of the first probe and the second probe; and a polymer bonded to the initiator, wherein the polymer is bonded to a plurality of signal generators, wherein the polymer comprises structural units derived from a polymer precursor comprising an atom transfer radical polymerization (ATRP) monomer, a ring opening metathesis polymerization (ROMP) monomer, or combinations thereof. |
地址 |
Niskayuna NY US |