发明名称 STABLE, LOW VISCOSITY ANTIBODY FORMULATION
摘要 <p>The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23°C. Also provided are methods of making and methods of using such antibody formulations.</p>
申请公布号 CA2885862(A1) 申请公布日期 2014.05.01
申请号 CA20132885862 申请日期 2013.10.23
申请人 MEDIMMUNE, LLC 发明人 BEE, JARED;SANTACROCE, PAUL;DU, JIALI;DIMITROVA, MARIANA
分类号 A61K47/34;A61K39/395;A61K47/18;A61K47/22 主分类号 A61K47/34
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