发明名称 |
STABLE, LOW VISCOSITY ANTIBODY FORMULATION |
摘要 |
<p>The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23°C. Also provided are methods of making and methods of using such antibody formulations.</p> |
申请公布号 |
CA2885862(A1) |
申请公布日期 |
2014.05.01 |
申请号 |
CA20132885862 |
申请日期 |
2013.10.23 |
申请人 |
MEDIMMUNE, LLC |
发明人 |
BEE, JARED;SANTACROCE, PAUL;DU, JIALI;DIMITROVA, MARIANA |
分类号 |
A61K47/34;A61K39/395;A61K47/18;A61K47/22 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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