发明名称 Montelukast 4-halobenzylamine salt and method for preparing montelukast sodium salt by using the same
摘要 Disclosed are a novel montelukast 4-halobenzylamine salt, and a method for preparing a montelukast sodium salt by using the same. In the disclosed method, a montelukast 4-halobenzylamine salt represented by Formula 2 or a montelukast sodium salt represented by Formula 1 is prepared by obtaining a compound represented by Formula 3 from a compound represented by Formula 5, in the same reactor, without an additional obtaining process. In Formula 2, X represents F, Cl, Br or I.
申请公布号 US8686151(B2) 申请公布日期 2014.04.01
申请号 US201213730168 申请日期 2012.12.28
申请人 DONG KOOK PHARM. CO., LTD. 发明人 KWON HYUK CHUL;RHO MAN DONG;CHA KYUNG HOI
分类号 C07D215/14 主分类号 C07D215/14
代理机构 代理人
主权项
地址