Uses and compositions for treatment of ankylosing spondylitis

摘要

The invention provides methods, uses and compositions for the treatment of ankylosing spondylitis (AS). The invention describes methods and uses for treating ankylosing spondylitis, wherein a TNFa inhibitor, such as a human TNFa antibody, or antigen-binding portion thereof, is used to reduce signs and symptoms of ankylosing spondylitis in a subject. Also described are methods for determining the efficacy of a TNFa inhibitor for treatment of ankylosing spondylitis in a subject.