发明名称 PURIFICATION METHOD OF PEPTIDYLGLYCINE ALPHA AMIDATING MONOOXYGENASE (PAM) IN HIGH PURITY BY LYSINE TAGGING AT C-TERMINAL OF PAM
摘要 This disclosure relates to recombinant alpha amidating enzyme protein that plays an important function in the body, and a method for preparing the same with high efficiency and high yield. To make human-derived peptide physiologically active, purified alpha amidating enzyme is required. Since highly purified human-derived alpha amidating enzyme, and a preparation method thereof according to the present invention may produce target protein in a large quantity while maintaining the activity, it may be useful for preparation of an agricultural or medical composition including alpha amidating hormone, calcitonin, growth hormone release factor, calcitonin gene related peptide, and various alpha amidated products.
申请公布号 KR101367869(B1) 申请公布日期 2014.02.28
申请号 KR20110145767 申请日期 2011.12.29
申请人 发明人
分类号 C07K1/18;C12N9/86;C12N15/63 主分类号 C07K1/18
代理机构 代理人
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