| 摘要 |
PROBLEM TO BE SOLVED: To provide specific spirocyclic compounds that are inhibitors of 11-&bgr; hydroxyl steroid dehydrogenase type 1 for treatment of diabetes, obesity and other diseases.SOLUTION: Compounds of the specified formula or a salt thereof acceptable as medicament is provided. [In the formula, R1 represents F, Cl, Br or I; and R2 and R3 are independently selected from H, a C1-6 alkyl and a C3-6 cycloalkyl.] |
