Method for the detection of glycans using polypeptides comprising the CD301 carbohydrate recognition domain

摘要

The present invention relates to a method for the detection of glycans in a tissue sample, which method comprises contacting the tissue sample with a recombinant polypeptide, said polypeptide comprising the carbohydrate recognition domain of a human CD301 polypeptide or a sequence having at least 80% sequence identity thereto, and detecting recombinant polypeptide that binds to said tissue sample. The invention also provides multimeric complexes comprising at least two of the above-described recombinant CD301 polypeptides and, optionally, an antibody which binds to said polypeptides.