BROAD BANDWIDTH MAGNETIC RESONANCE SPECTROSCOPY AT HIGH STATIC (B0) MAGNETIC FIELD USING POLARIZATION TRANSFER

摘要

A magnetic resonance (MR) generating a static (BO) magnetic field of 5 Tesla or higher controller is configured to control an MR scanner to perform an MR sequence (14) including: performing an excitation/localization sub-sequence (30) on a subject disposed in the static (BO) magnetic field generated by the MR scanner to excite 1H polarization in a selected spatial region of the subject; performing 5 a polarization transfer sub-sequence (32) to transfer localized 1H polarization generated by the excitation/localization sub-sequence to a selected species of non-proton nuclei; and performing a magnetic resonance spectroscopy (MRS) readout sub-sequence (40) to acquire MRS data for the selected species of non-proton nuclei in the selected spatial region of the subject. The polarization transfer sub-sequence includes a pair of phase 10 distortion canceling trapezoidal 180� refocusing pulses (36, 37) operating on the selected species of non-proton nuclei.