发明名称 |
ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS |
摘要 |
The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof; the present invention also relates to a composition comprising a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents. The present invention also relates to use of a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, preventing or treating a disease or disorder associated with apoptosis; especially use for protecting cardiomyocyte, preventing or treating a disease or disorder associated with cardiomyocyte apoptosis. |
申请公布号 |
EP2573078(A4) |
申请公布日期 |
2013.11.20 |
申请号 |
EP20100851188 |
申请日期 |
2010.05.14 |
申请人 |
CHINESE PLA GENERAL HOSPITAL |
发明人 |
HE, KUNLUN;LI, SONG;ZHONG, WU;LIU, JUAN;WANG, LILI;LI, XIN;HU, GUOLIANG;WANG, JIE;LONG, LONG;XIAO, JUNHAI;ZHENG, ZHIBING;LI, WEI;LI, RUIJUN;LIU, CHUNLEI;TANG, JIE |
分类号 |
C07D333/04;A61K31/17;A61K31/381;A61K31/435;A61K31/4709;A61K31/496;A61K31/5377;A61P9/00;A61P43/00;C07C335/12;C07D295/21;C07D333/10;C07D409/12 |
主分类号 |
C07D333/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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