发明名称 BIR domain binding compounds
摘要 The present invention is directed towards an isomer, an enantiomer, a diastereoisomer, or a tautomer of a pyrrolidine compound represented by Formula I: in which the substituents R1, R1a, R2, R2a, R3, A and Q are defined herein; or a prodrug, or a salt thereof, and which bind to IAP BIR domains. In particular, the compounds are useful in treating proliferative disorders such as cancer.
申请公布号 US8575113(B2) 申请公布日期 2013.11.05
申请号 US20100825197 申请日期 2010.06.28
申请人 JARVIS SCOTT;BOUDREAULT ALAIN;BUREAU PATRICK;JAQUITH JAMES B.;LAURENT ALAIN;LABIT DELPHINE;PHARMASCIENCE INC. 发明人 JARVIS SCOTT;BOUDREAULT ALAIN;BUREAU PATRICK;JAQUITH JAMES B.;LAURENT ALAIN;LABIT DELPHINE
分类号 A61K38/06;A61K38/00;A61K38/07;A61P43/00 主分类号 A61K38/06
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