发明名称 |
Nucleic acids encoding SOX10 promoter and methods to isolate SOX10 expressing cells |
摘要 |
DNA enhancer sequences are provided for use in constructs to identify early stage embryonic cells. The enhancer sequences can be used in parallel with short-hairpin RNA in a vector construct for endogenously regulated gene knockdowns. The disclosed enhancer sequences can be used to isolate a selected population of early stage embryonic cells.
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申请公布号 |
US8524875(B2) |
申请公布日期 |
2013.09.03 |
申请号 |
US20090645431 |
申请日期 |
2009.12.22 |
申请人 |
SAUKA-SPENGLER TATJANA;MCKEOWN SONJA J.;BETANCUR PAOLA;BRONNER MARIANNE;CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
SAUKA-SPENGLER TATJANA;MCKEOWN SONJA J.;BETANCUR PAOLA;BRONNER MARIANNE |
分类号 |
C12Q1/68;C07H21/04;C12N15/00;C12P21/06;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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