发明名称 |
PROCESS FOR THE SYNTHESIS OF CARBONUCLEOSIDE AND INTERMEDIATES FOR USE THEREIN |
摘要 |
Disclosed is a process for preparing a carbonucleoside of formula (1) and intermediates for use therein. The process involves the step of reacting a compound of formula (2) with a compound of formula (3) under Mitsunobu-type reaction conditions to obtain a compound of formula (4), wherein PG1, PG2, PG3 and PG4 are protecting groups. The compound of formula (4) is deprotected to form the compound of formula (1), as shown below.
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申请公布号 |
US2013144058(A1) |
申请公布日期 |
2013.06.06 |
申请号 |
US201113700259 |
申请日期 |
2011.05.30 |
申请人 |
ALBERICO DINO;CLAYTON JOSHUA;DIXON CRAIG;GORIN BORIS;ALPHORA RESEARCH INC. |
发明人 |
ALBERICO DINO;CLAYTON JOSHUA;DIXON CRAIG;GORIN BORIS |
分类号 |
C07D473/02;A61K31/522;C07D473/18;C07H19/16 |
主分类号 |
C07D473/02 |
代理机构 |
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代理人 |
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主权项 |
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