发明名称 |
ANTIBODY TO CD40 |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide an isolated antibody or antigen-binding portion thereof that specifically binds to human CD40 and functions as a CD40 agonist. <P>SOLUTION: The antibody or antigen-binding portion thereof comprises an isolated nucleic acid molecule including a nucleic acid sequence that encodes a heavy chain or an antigen-binding portion thereof or the light chain or an antigen-binding portion thereof of a human anti-CD40 antibody, wherein nucleic acids, that encode fragments of the heavy chains and the light chains from a hybridoma cell that produce anti CD40 monoclonal antibodies derived from mice immunized with human CD40, are subjected to cloning and sequencing. <P>COPYRIGHT: (C)2013,JPO&INPIT |
申请公布号 |
JP2013099333(A) |
申请公布日期 |
2013.05.23 |
申请号 |
JP20120270885 |
申请日期 |
2012.12.12 |
申请人 |
PFIZER PRODUCTS INC;AMGEN FREMONT INC |
发明人 |
BEDIAN VAHE;GLADUE RONALD P;CORVALAN JOSE;JIA XIAO-CHI;FENG XIAO |
分类号 |
A01H5/00;C12N15/09;A01H1/00;A01K67/027;A61K31/7088;A61K35/76;A61K39/395;A61K48/00;A61P13/08;A61P13/10;A61P35/00;A61P35/02;A61P43/00;C07K;C07K16/28;C07K16/40;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N15/02;C12N15/12;C12P21/02;C12P21/08 |
主分类号 |
A01H5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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