摘要 |
This disclosure relates to new tetracyclic compounds that may be used to modulate a histamine receptor in an individual. The compounds in one embodiment are tetracyclic [4,3- b]indoles. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder. |
申请人 |
MEDIVATION TECHNOLOGIES, INC. |
发明人 |
USTINOV, ANATOLY KONSTANTINOVICH;PROTTER, ANDREW ASHER;BEZNOSKO, BOGDAN KONSTANTINOVICH;HUNG, DAVID T.;GRIGORIEV, VLADIMIR VIKTOROVICH;JAIN, RAJENDRA;CHAKRAVARTY, SARVAJIT;BACHURIN, SERGEY OLEGOVICH;DUGAR, SUNDEEP;SHEVTSOVA, ELENA FEOFANOVNA |