发明名称 Antibacterial compositions
摘要 Compounds of formula (I) have antibacterial activity: wherein: m is 0 or 1; Q is hydrogen or cyclopropyl; Alk is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (—O—), thioether (—S—) or amino (—NR)— link, wherein R is hydrogen, —CN or C1-C3 alkyl; X is —C(═O)NR6—, —S(O)NR6—, —C(═O)O— or —S(═O)O— wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, -Cyc, or —(C1-C3 alkyl)-Cyc wherein Cyc is optionally substituted monocyclic carbocyclic or heterocyclic having 3-7 ring atoms; Z is N or CH, or CF; R2 and R3 are as defined in the description.
申请公布号 US8389516(B2) 申请公布日期 2013.03.05
申请号 US201113154592 申请日期 2011.06.07
申请人 HAYDON DAVID JOHN;CZAPLEWSKI LLOYD GEORGE;PALMER NICHOLAS JOHN;MITCHELL DALE ROBERT;ATHERALL JOHN FREDERICK;STEELE CHRISTOPHER RICHARD;LADDUWAHETTY TAMARA;BIOTA EUROPE LIMITED 发明人 HAYDON DAVID JOHN;CZAPLEWSKI LLOYD GEORGE;PALMER NICHOLAS JOHN;MITCHELL DALE ROBERT;ATHERALL JOHN FREDERICK;STEELE CHRISTOPHER RICHARD;LADDUWAHETTY TAMARA
分类号 A61K31/5377;A61K31/428;A61K31/429;A61K31/4436;A61K31/496;A61K31/497;A61K31/501;A61K31/506;C07D239/42 主分类号 A61K31/5377
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