The present invention relates to antagonist antibodies or fragments thereof that bind to human OX40. More specifically, the present invention relates to an antagonist antibody or fragment thereof that binds to human OX40 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 1, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 2, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 3; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 4, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 6.
申请公布号
WO2013008171(A1)
申请公布日期
2013.01.17
申请号
WO2012IB53502
申请日期
2012.07.09
申请人
GLENMARK PHARMACEUTICALS S.A.;ATTINGER, ANTOINE;BLEIN, STANISLAS;BACK, JONATHAN ALBERT;LISSILAA, RAMI;HOU, SAMUEL
发明人
ATTINGER, ANTOINE;BLEIN, STANISLAS;BACK, JONATHAN ALBERT;LISSILAA, RAMI;HOU, SAMUEL