发明名称 |
COMPOSITION FOR PROMOTING THE DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELL |
摘要 |
PURPOSE: A composition with Nelumbinis Semen extracts as an active ingredient for promoting the differentiation of adipocyte in human mesenchymal stem cell is provided to promote differentiating the adipocyte from a human mesenchymal stem cell to produce lipid droplet, enhance the electricity and the volume of skin and reduce wrinkles. CONSTITUTION: A composition for skin external application for promoting the differentiation of adipocyte contains Nelumbinis Semen extracts as an active ingredient. The composition promotes differentiating adipocyte from a mesenchymal stem cell. The mesenchymal stem cell is a human mesenchymal cell. The composition increases adipocyte tissue. For the total weight of the composition, a Nelumbinis Semen extract weighs ranging from 0.001 to 30%. The composition enhances the volume of skin and the elasticity of skin, and reduces skin wrinkles. A pharmaceutical composition for promoting the differentiation of a adipocyte cell contains Nelumbinis Semen as an active ingredient. A Nelumbinis Semen extract is administered from 0.001mg /kg /day-2000mg /kg /day. [Reference numerals] (AA) Relative revelation amount; (BB) Negative control group; (CC) Ligustri Fructus; (DD) Veratri Rhizoma Et Radix; (EE) Forsythiae Fructus; (FF) Nelumbo semen |
申请公布号 |
KR20120140450(A) |
申请公布日期 |
2012.12.31 |
申请号 |
KR20110060194 |
申请日期 |
2011.06.21 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
SHIN, DONG WOOK;NOH, MIN SOO;PARK, SOO NAM |
分类号 |
A61K36/62;A61P17/00;C12N5/0775 |
主分类号 |
A61K36/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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